Tofarus gel 10gm (Tofacitinb gel 2%)

Description

1. Tofarus Gel, which contains Tofacitinib 2% in a gel base, is a brand that has introduced this medication for the first time in India. It is primarily used in the treatment of several dermatological conditions such as psoriasis, vitiligo, alopecia areata, and atopic dermatitis.
2. Tofacitinib, in its oral form, is also indicated for the treatment of rheumatoid arthritis, active psoriatic arthritis, ulcerative colitis, ankylosing spondylitis, and polyarticular course juvenile idiopathic arthritis.Vitiligo is a condition characterized by the loss of pigmentation in certain areas of the skin, resulting in white patches. The interferon-gamma signaling pathway is thought to play a crucial role in the progression of vitiligo. The JAK receptors are involved in this pathway.
3. Tofacitinib, being a JAK receptor inhibitor, can block this pathway and potentially impede the progression of the disease. By blocking the pathway, it may also help stimulate repigmentation of the affected areas.It’s important to note that while Tofacitinib is being studied for use in vitiligo, it may not be officially approved for this indication in all countries. It’s always advisable to consult with a healthcare professional who can provide personalized advice and guidance regarding the appropriate treatment options for your specific condition.